High-throughput and high-purity separation of malignant tumor cells in pleural and peritoneal effusions using interfacial elasto-inertial microfluidics

نویسندگان

چکیده

The efficient separation of exfoliated malignant tumor cells (MTCs) from pleural and peritoneal effusions is critical for improving the detection sensitivity reducing time-consuming cytological assessment. Herein, an...

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Inertial Microfluidics: High-throughput Focusing and Separation of Cells and Particles

Here we describe a continuous particle focusing and separation system taking advantage of microscale physics but with throughput comparable to macroscale systems. The device simply consists of a single asymmetrically curved channel with tuned dimensions and flow conditions. Unlike mechanical filters, deformable and rigid particles are shown to focus and separate with equal efficiency. Additiona...

متن کامل

High-throughput rare cell separation from blood samples using steric hindrance and inertial microfluidics.

The presence and quantity of rare cells in the bloodstream of cancer patients provide a potentially accessible source for the early detection of invasive cancer and for monitoring the treatment of advanced diseases. The separation of rare cells from peripheral blood, as a "virtual and real-time liquid biopsy", is expected to replace conventional tissue biopsies of metastatic tumors for therapy ...

متن کامل

the relationship between academic self-concept and academic achievement in english and general subjects of the students of high school

according to research, academic self-concept and academic achievement are mutually interdependent. in the present study, the aim was to determine the relationship between the academic self-concept and the academic achievement of students in english as a foreign language and general subjects. the participants were 320 students studying in 4th grade of high school in three cities of noor, nowshah...

Inertial microfluidics in parallel channels for high-throughput applications.

Passive particle focusing based on inertial microfluidics was recently introduced as a high-throughput alternative to active focusing methods that require an external force-field to manipulate particles. In this study, we introduce inertial microfluidics in flows through straight, multiple parallel channels. The scalable, single inlet and two outlet, parallel channel system is enabled by a nove...

متن کامل

Pinched flow coupled shear-modulated inertial microfluidics for high-throughput rare blood cell separation.

Blood is a highly complex bio-fluid with cellular components making up >40% of the total volume, thus making its analysis challenging and time-consuming. In this work, we introduce a high-throughput size-based separation method for processing diluted blood using inertial microfluidics. The technique takes advantage of the preferential cell focusing in high aspect-ratio microchannels coupled wit...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Sensors & diagnostics

سال: 2023

ISSN: ['2635-0998']

DOI: https://doi.org/10.1039/d3sd00107e